Guanidinoacetate Methyltransferase Deficiency (GAMT) is a mutation in the GAMT gene that makes the enzyme that creates creatine, resulting in a shortage of creatine.
Treatment with oral supplementation is available and effective, if initiated early for GAMT patients. Supplementation may include Creatine Monohydrate, L-ornithine and Sodium Benzoate.
Dosing and supplementation may vary from patient to patient. The ACD does not recommend or advise any supplementation to be taken without physician supervision.